Vollständige Bibliografie aus Xu Fans CV: 104 Aufsätze (dedupliziert) und 15 Software-Eintragungen.
RESEARCH TIMELINE · 2006—2026
akademische Zeitachse
25 Forschungseinträge, zeitlich geordnet wie belegt. Drei Kurzdossiers führen ausführlich ein; die übrigen behalten sachliche Kurzfassungen und Quellenlinks; die vollständige CV-Liste folgt unten.
Die Updates stellen persönliche und gemeinsame Forschung dar; Danksagungen belegen nur den Austausch; nichts davon ist Firmen-F&E.
Chinesischsprachige Literatur zum Fortschritt der Zelltransplantation bei Rückenmarkverletzungen, hier als Titelaufnahme geführt.
Belege stützen nur den CV-Eintrag; der Zeitschriftenlink lieferte keinen Treffer, daher keine Ergebnisse.
Siehe vollständige CV-Liste unten; die Unterlagen tragen nur bibliografische Einträge.
Einträge & Belegumfang
Xu F et al (2006) The progress of cell transplantation in spinal cord injury, J Sichuan Physiology,28(3),123-125(Chinese)
Eintrag P0246 · CV-Jahr 2006 · Datumsgrundlage cv_listed_year_only. Daten werden mit der verfügbaren Genauigkeit (Jahr/Monat/Tag) angezeigt.
Kein lesbares Abstract; aus Titeln alone werden keine Schlüsse geschrieben.
Jahreseinträge
Forschungs-Updatesnur CV-Eintrag, siehe Original
Rückenmarkmodelle und Neurofunktion: frühe Hinweise
Chinesischsprachige Literatur zu Rückenmarkmodellen und Funktionsbewertung, hier als Titelaufnahme geführt.
Tiermodell-Hinweise ersetzen keine klinischen Belege am Menschen.
Siehe vollständige CV-Liste unten; die Unterlagen tragen nur bibliografische Einträge.
Einträge & Belegumfang
Xu F et al (2007) Establishment of spinal cord injury models and its evaluation of neural function after spinal cord injury ,J Trauma Surgery, 1:91-93 (Chinese)
Eintrag P0244 · CV-Jahr 2007 · Datumsgrundlage cv_listed_year_only. Daten werden mit der verfügbaren Genauigkeit (Jahr/Monat/Tag) angezeigt.
Kein lesbares Abstract; aus Titeln alone werden keine Schlüsse geschrieben.
Construction and validation of a systematic ethogram of Macaca fascicularis in a free enclosure.
Eintrag P0241 · CV-Jahr 2012 · Datumsgrundlage epub. Daten werden mit der verfügbaren Genauigkeit (Jahr/Monat/Tag) angezeigt.
Paper-Abstract (Original)
Behavioral studies in non-human primates have become ideal models for further investigations into advanced cognitive function in humans. To date, there is no systematic ethogram of the cynomolgus monkey (Macaca fascicularis) in a free enclosure. In a field observation of 6012 subjects, 107 distinct behaviors of M. fascicularis were preliminarily described. 83 of these behaviors were then independently validated through a randomized cohort and classified into 12 behavioral categories. 53 of these behaviors were then selected to accurately reflect the daily mundane activity of the species in a free enclosure. These findings systematically document the behavior of M. fascicularis in a free enclosure for use in further investigations.
Publikationsdatum
Forschungs-UpdatesPloS one
Depressionsähnliches Verhalten bei sozialer Isolation
Soziale und zusätzliche visuelle Isolation führten zu abgestuften Verhaltensänderungen.
Depressionsähnliches Tierverhalten ist keine menschliche Diagnose; Autorenfolge zu prüfen.
Depression-like behavioral phenotypes by social and social plus visual isolation in the adult female Macaca fascicularis.
Eintrag P0239 · CV-Jahr 2013 · Datumsgrundlage article_pub_date. Daten werden mit der verfügbaren Genauigkeit (Jahr/Monat/Tag) angezeigt.
Paper-Abstract (Original)
Major depressive disorder (MDD) is a debilitating psychiatric mood disorder that affects millions of individuals globally. Our understanding of the biological basis of MDD is poor, and current treatments are ineffective in a significant proportion of cases. This current situation may relate to the dominant rodent animal models of depression, which possess translational limitations due to limited homologies with humans. Therefore, a more homologous primate model of depression is needed to advance investigation into the pathophysiological mechanisms underlying depression and to conduct pre-clinical therapeutic trials. Here, we report two convenient methods--social isolation and social plus visual isolation--which can be applied to construct a non-human primate model of depression in the adult female cynomolgus monkey (Macaca fascicularis). Both social and social plus visual isolation were shown to be effective in inducing depression-like behavior by significantly reducing socially dominant aggressive conflict behavior, communicative behavior, sexual behavior, and parental behavior. The addition of visual isolation produced more profound behavioral changes than social isolation alone by further reducing parental behavior and sexual behavior. Thus, the degree of behavioral pathology may be manipulated by the degree of isolation. These methods can be applied to construct a non-human primate model of depression in order to assess physiological, behavioral, and social phenomena in a controlled laboratory setting.
Publikationsdatum
Forschungs-UpdatesPloS one
Mutter-Kind-Interaktion und depressionsähnliches Verhalten
Verblindete Verhaltenskodierung vergleich depressive und gesunde Tiere.
Schlüsse gelten nur für Tier und Beobachtung — nicht als menschliche Ansteckung.
The mutual influences between depressed Macaca fascicularis mothers and their infants.
Eintrag P0236 · CV-Jahr 2014 · Datumsgrundlage article_pub_date. Daten werden mit der verfügbaren Genauigkeit (Jahr/Monat/Tag) angezeigt.
Paper-Abstract (Original)
Objective To assess the influence of infant rearing on the behavior of depressed adult female Macaca fascicularis and the influence of depressed infant-rearing adult female Macaca fascicularis on their infants in a free enclosure environment. Methods Here, 20 depressed subjects and then 20 healthy subjects were randomly selected from a total population of 1007 adult female Macaca fascicularis subjects. Four depressed subjects and eight healthy subjects were rearing infants. By focal observation, three trained observers video-recorded the selected subjects over a total observational period of 560 hours. The video footage was analyzed by qualified blinded analysts that coded the raw footage into quantitative behavioral data (i.e., durations of 53 pre-defined behavioral items across 12 behavioral categories) for statistical analysis. Results Between infant-rearing and non-rearing healthy subjects, ten differential behaviors distributed across five behavioral categories were identified. Between infant-rearing and non-rearing depressed subjects, nine behaviors distributed across five behavioral categories were identified. Between infant-rearing healthy and infant-rearing depressed subjects, fifteen behaviors distributed across six behavioral categories were identified. Conclusion Infant-rearing depressed adult female Macaca fascicularis subjects may have a worse psychological status as compared to non-rearing depressed counterparts. Infant rearing may negatively influence depressed Macaca fascicularis mothers. Infant-rearing depressed subjects were less adequate at raising infants as compared to infant-rearing healthy subjects. Thus, maternal depression in this macaque species may negatively impact infatile development, which is consistent with previous findings in humans.
Publikationsdatum
Forschungs-UpdatesScientific reports
Spontan depressive Phänotypen in sozialer Haltung
Beschreibung spontaner depressiver Phänotypen und metabolischer Unterschiede, mit Modelldiskussion.
Die Ketamin-Prüfung belegte keine Prädiktionsvalidität; keine Aussage als vollständig validiert.
Macaques exhibit a naturally-occurring depression similar to humans.
Eintrag P0233 · CV-Jahr 2015 · Datumsgrundlage article_pub_date. Daten werden mit der verfügbaren Genauigkeit (Jahr/Monat/Tag) angezeigt.
Paper-Abstract (Original)
Rodent models have dominated preclinical investigations into the mechanisms of depression. However, these models-which rely on subjecting individual rodents to physical stressors - do not realistically resemble the etiopathological development of depression, which occurs naturally in a social context. A non-human primate model that better reflects the social ethological aspects of depression would be more advantageous to investigating pathophysiological mechanisms and developing antidepressant therapeutics. Here, we describe and model a naturally-occurring depressive state in a non-human primate species, the cynomolgus monkey (Macaca fascicularis), in a realistic social ethological context and associate the depressed behavioral phenotype with significant serum metabolic perturbations. One to two subjects per stable social colony (17-22 subjects) manifested a depressive phenotype that may be attributed to psychosocial stress. In accordance with rodent and human studies, the serum metabolic phenotype of depressed and healthy subjects significantly differed, supporting the model's face validity. However, application of the fast-acting antidepressant ketamine failed to demonstrate predictive validity. This study proposes a non-human primate depression model in a realistic social ethological context that can better approximate the psychosocial stressors underlying depression.
Publikationsdatum
Forschungs-UpdatesBMC bioinformatics
Co-Expression und Regulation zweier Depressionszustände
Transkriptome peripherer Lymphozyten wurden zwischen Major- und subklinischer Depression verglichen.
Rechenanalyse ist kein klinisches Klassifikationswerkzeug; keine Firma-Diagnostik.
Differential co-expression and regulation analyses reveal different mechanisms underlying major depressive disorder and subsyndromal symptomatic depression.
Eintrag P0234 · CV-Jahr 2015 · Datumsgrundlage epub. Daten werden mit der verfügbaren Genauigkeit (Jahr/Monat/Tag) angezeigt.
Paper-Abstract (Original)
Background Recent depression research has revealed a growing awareness of how to best classify depression into depressive subtypes. Appropriately subtyping depression can lead to identification of subtypes that are more responsive to current pharmacological treatment and aid in separating out depressed patients in which current antidepressants are not particularly effective. Differential co-expression analysis (DCEA) and differential regulation analysis (DRA) were applied to compare the transcriptomic profiles of peripheral blood lymphocytes from patients with two depressive subtypes: major depressive disorder (MDD) and subsyndromal symptomatic depression (SSD). Results Six differentially regulated genes (DRGs) (FOSL1, SRF, JUN, TFAP4, SOX9, and HLF) and 16 transcription factor-to-target differentially co-expressed gene links or pairs (TF2target DCLs) appear to be the key differential factors in MDD; in contrast, one DRG (PATZ1) and eight TF2target DCLs appear to be the key differential factors in SSD. There was no overlap between the MDD target genes and SSD target genes. Venlafaxine (Efexor™, Effexor™) appears to have a significant effect on the gene expression profile of MDD patients but no significant effect on the gene expression profile of SSD patients. Conclusion DCEA and DRA revealed no apparent similarities between the differential regulatory processes underlying MDD and SSD. This bioinformatic analysis may provide novel insights that can support future antidepressant R&D efforts.
Publikationsdatum
Forschungs-UpdatesNeuropsychiatric disease and treatment
Evidenzvergleich tiefer Hirnstimulationsziele bei Parkinson
Meta-Analyse (13 Studien, 1148 Patienten) verglich STN- und GPi-Stimulation.
Endpunkte haben Abwägungen; keine persönliche Therapieempfehlung, keine Medizintechnik des Unternehmens.
Deep brain stimulation of pallidal versus subthalamic for patients with Parkinson's disease: a meta-analysis of controlled clinical trials.
Eintrag P0231 · CV-Jahr 2016 · Datumsgrundlage article_pub_date. Daten werden mit der verfügbaren Genauigkeit (Jahr/Monat/Tag) angezeigt.
Paper-Abstract (Original)
Background Parkinson's disease (PD) is a common neurodegenerative disorder that affects many people every year. Deep brain stimulation (DBS) is an effective nonpharmacological method to treat PD motor symptoms. This meta-analysis was conducted to evaluate the efficacy of subthalamic nucleus (STN)-DBS versus globus pallidus internus (GPi)-DBS in treating advanced PD. Methods Controlled clinical trials that compared STN-DBS to GPi-DBS for short-term treatment of PD in adults were researched up to November 2015. The primary outcomes were the Unified Parkinson's Disease Rating Scale Section (UPDRS) III score and the levodopa-equivalent dosage (LED) after DBS. The secondary outcomes were the UPDRS II score and the Beck Depression Inventory (BDI) score. Results Totally, 13 studies containing 1,148 PD patients were included in this meta-analysis to compare STN-DBS versus GPi-DBS. During the off-medication state, the pooled weighted mean difference (WMD) of UPDRS III and II scores were -2.18 (95% CI =-5.11 to 0.74) and -1.96 (95% CI =-3.84 to -0.08), respectively. During the on-medication state, the pooled WMD of UPDRS III and II scores were 0.15 (95% CI =-1.14 to 1.44) and 1.01 (95% CI =0.12 to 1.89), respectively. After DBS, the pooled WMD of LED and BDI were -254.48 (95% CI =-341.66) and 2.29 (95% CI =0.83 to 3.75), respectively. Conclusion These results indicate that during the off-medication state, the STN-DBS might be superior to GPi-DBS in improving the motor function and activities of daily living for PD patients; but during the on-medication state, the opposite result is observed. Meanwhile, the STN-DBS is superior at reducing the LED, whereas the GPi-DBS shows a significantly greater reduction in BDI score after DBS.
Publikationsdatum
Forschungs-UpdatesEdelweiss Psychiatry Open Access
Standpunktartikel zur Natur depressiver Störungen
Der Artikel diskutiert Depressionsmechanismen über Medikamente, Genexpression, Systembiologie und Schaltkreise.
Gemäß Volltext; Diskussionen werden nicht zu neuen Experimenten umgedeutet.
Meta‑analysis of current chemotherapy regimens in advanced pancreatic cancer to prolong survival and reduce treatment‑associated toxicities.
Eintrag P0227 · CV-Jahr 2019 · Datumsgrundlage article_pub_date. Daten werden mit der verfügbaren Genauigkeit (Jahr/Monat/Tag) angezeigt.
Paper-Abstract (Original)
Unresectable advanced pancreatic cancer (APC) is a highly lethal malignancy. Although numerous chemotherapeutic regimens are available, evidence regarding the survival extension, the life quality improvement, the associated risks and occurrence rates of adverse effects, is required. The effects of 19 chemotherapy regimens on survival and treatment‑associated toxicities in the context of APC treatment were comparatively assessed. A total of 23 randomized controlled trials were included in this network meta‑analysis. For overall survival, five regimens, Gemcitabine (Gem)+radiotherapy (Radio), Gem+cisplatin (Cis), Gem+erlotinib (Erl)+bevacizumab (Bev), Gem+capecitabine (Cap)+Erl, and Gem+exatecan, were the most effective treatments, according to their respective high surface under the cumulative ranking (SUCRA) probabilities. Regarding the progression‑free survival, five regimens, including Gem+Radio, Gem+Erl+Bev, Gem+Cis, Gem+Cap+Erl and Gem+pemetrexed, were the most effective treatments based on their SUCRA probabilities. Each regimen exhibited advantages and disadvantages, and 14 common treatment‑associated toxicities were present in different proportions. The three principal toxic effects included haematological, gastrointestinal and constitutional symptoms. To improve survival, chemotherapy regimens with high SUCRA probabilities require prioritizing. Although treatment‑associated toxicities are unavoidable, the regimens presented toxicities in distinct proportions. Therefore, clinicians should assess the disease status of the patients, and balance the benefits and risks of the selected treatment.
Jahreseinträge
Forschungs-UpdatesArchives of Biomedical and Clinical Research
Hinweise zu Stimmveränderungen bei Parkinson
Der Artikel reviewing Stimme, Artikulation und Stimmlippenbewegung bei Parkinson.
Gemäß Verlagsvolltext: Früherkennungspotenzial, kein validiertes Screening.
The physical significance of acoustic parameters and its clinical significance of dysarthria in Parkinson's disease.
Eintrag P0217 · CV-Jahr 2020 · Datumsgrundlage epub. Daten werden mit der verfügbaren Genauigkeit (Jahr/Monat/Tag) angezeigt.
Paper-Abstract (Original)
Dysarthria is universal in Parkinson's disease (PD) during disease progression; however, the quality of vocalization changes is often ignored. Furthermore, the role of changes in the acoustic parameters of phonation in PD patients remains unclear. We recruited 35 PD patients and 26 healthy controls to perform single, double, and multiple syllable tests. A logistic regression was performed to differentiate between protective and risk factors among the acoustic parameters. The results indicated that the mean f0, max f0, min f0, jitter, duration of speech and median intensity of speaking for the PD patients were significantly different from those of the healthy controls. These results reveal some promising indicators of dysarthric symptoms consisting of acoustic parameters, and they strengthen our understanding about the significance of changes in phonation by PD patients, which may accelerate the discovery of novel PD biomarkers.
Publikationsdatum
Forschungs-UpdatesInternational Journal of Information Technology
Hinweise zu einem Gesundheitsdaten-Framework
CV und Crossref bestätigen eine PowerShell-basierte Rahmenarbeit; ohne Volltext keine Leistungs- oder Einsatzfälle.
Online 2020 und Heft 2021 sind beide anzugeben; keine Umdeutung als Projektlieferung.
Fast and accurate automated recognition of the dominant cells from fecal images based on Faster R-CNN.
Eintrag P0211 · CV-Jahr 2021 · Datumsgrundlage article_pub_date. Daten werden mit der verfügbaren Genauigkeit (Jahr/Monat/Tag) angezeigt.
Paper-Abstract (Original)
Fecal samples can easily be collected and are representative of a person's current health state; therefore, the demand for routine fecal examination has increased sharply. However, manual operation may pollute the samples, and low efficiency limits the general examination speed; therefore, automatic analysis is needed. Nevertheless, recognition exhaustion time and accuracy remain major challenges in automatic testing. Here, we introduce a fast and efficient cell-detection algorithm based on the Faster-R-CNN technique: the Resnet-152 convolutional neural network architecture. Additionally, a region proposal network and a network combined with principal component analysis are proposed for cell location and recognition in microscopic images. Our algorithm achieved a mean average precision of 84% and a 723 ms detection time per sample for 40,560 fecal images. Thus, this approach may provide a solid theoretical basis for real-time detection in routine clinical examinations while accelerating the process to satisfy increasing demand.
Publikationsdatum
Forschungs-UpdatesCNS neuroscience & therapeutics
Kopftremor bei Phonation und Parkinson-Schwere
18 Patienten und 18 Gesunde absolvierten Phonationstests; videobasierte Kopfbewegung wurde mit dem Schweregrad verrechnet.
Assoziation allein belegt keine Früherkennung; online 2021, Heft 2022.
Correlation between head tremble and the severity of Parkinson's disease.
Eintrag P0204 · CV-Jahr 2021 · Datumsgrundlage crossref_published-online. Daten werden mit der verfügbaren Genauigkeit (Jahr/Monat/Tag) angezeigt.
Paper-Abstract (Original)
Introduction Parkinson's (PD) is a common degenerative disease of the central nervous system. It affects more than 6 million individuals worldwide. The typical clinical manifestations include static tremor, slow movement, and unstable posture. However, the correlation between head tremor and the severity of PD remains unclear. Methods In the current study, 18 patients and 18 healthy subjects were recruited to undergo a phonation test. Noldus facereader 7.0 software was used to analyze the range of head trembling between the two groups. Results The data revealed that patients with PD had significant differences in the x-, y-, and z-axis of head movement with respect to the specific pronunciation syllables compared with the normal group. Moreover, the head movement of the patients with PD was positively correlated with the severity of the disease in the single, double, and multiple syllable tests. In the phonetic test, the head displacement of patients with PD was significantly greater than that of healthy individuals, and the displacement range was positively correlated with the severity of the disease. Conclusion These pieces of evidence suggested that the measurement of head displacement assists the early diagnosis and severity of the disease.
Publikationsdatum
Forschungs-UpdatesFrontiers in cardiovascular medicine
S3 und Auswurffraktion: verschiedene Beweisgrenzen
Das systematische Review (19 Studien, 5614 Personen) verglich S3 mit der Auswurffraktion.
S3 allein ist wenig sensitiv; Herztöne ersetzen keinen Ultraschall.
A systemic review and meta-analysis comparing the ability of diagnostic of the third heart sound and left ventricular ejection fraction in heart failure.
Eintrag P0194 · CV-Jahr 2022 · Datumsgrundlage crossref_published-online. Daten werden mit der verfügbaren Genauigkeit (Jahr/Monat/Tag) angezeigt.
Paper-Abstract (Original)
Objective This study aimed to compare the sensitivity and specificity of diagnosis between the third heart sound (S3) and left ventricular ejection fraction (LVEF) in heart failure (HF). Methods Relevant studies were searched in PubMed, SinoMed, China National Knowledge Infrastructure, and the Cochrane Trial Register until February 20, 2022. The sensitivity, specificity, likelihood ratio (LR), and diagnostic odds ratio (DOR) were pooled. The symmetric receiver operator characteristic curve (SROC) and Fagan's nomogram were drawn. The source of heterogeneity was explored by meta-regression and subgroup analysis. Results A total of 19 studies, involving 5,614 participants, were included. The combined sensitivity of S3 was 0.23 [95% confidence interval (CI) (0.15-0.33), specificity was 0.94 [95% CI (0.82-0.98)], area under the SROC curve was 0.49, and the DOR was 4.55; while the sensitivity of LVEF was 0.70 [95% CI (0.53-0.83)], specificity was 0.79 [95% CI (0.75-0.82)], area under the SROC curve was 0.79, and the DOR was 8.64. No publication bias was detected in Deeks' funnel plot. The prospective design, partial verification bias, and blind contributed to the heterogeneity in specificity, while adequate description of study participants contributed to the heterogeneity in sensitivity. In Fagan's nomogram, the post-test probability was 48% when the pre-test probability was set as 20%, while in LVEF, the post-test probability was 45% when the pre-test probability was set as 20%. Conclusion The use of S3 alone presented lower sensitivity in diagnosing HF compared with LVEF, whereas it was useful in early pathological assessment.
Publikationsdatum
Wissenschaftsbilder & PaperCancer cell international
Pankreaskarzinom-Fortschritt und Illustrationsbezüge
Das Review behandelt präoperative Therapie, Chirurgie und Systemtherapie; die entsprechende Illustration in der Werkgalerie (Chirurgie-Holzschnitte in Rot-Schwarz) geht auf Figure 2 der Arbeit zurück.
Originalunterschrift "Drawn by FFL", Beitrag "LFF drew the images", Autorliste Fangfang Liu — keine Firmen-Rechte ableitbar.
Pancreatic cancer is a rare but fatal disease. Patients present advanced disease due to the lack of or typical symptoms when the tumor is still localized. A high-quality image processing system has been in practice to detect the pancreatic tumor and determine the possibility of surgery, and preoperative methods, such as ERCP are increasingly used to complement the staging modality. Pancreaticoduodenectomy is one of the complicated surgeries with potential morbidity. The minimally invasive pancreatic resections, both robot-assisted and laparoscopic, have become a part of standard surgical practice worldwide over the last decade. Moreover, advancements in adjuvant chemotherapy have improved the long-term outcomes in current clinical practice. The systemic conservative treatment, including targeted agents, remains the mainstay of treatment for patients with advanced disease. An increasing number of studies are focused on modulating the pancreatic tumor microenvironment to improve the efficacy of the immunotherapeutic strategies. Herein, the role of preoperative therapy, the novel surgical strategy, and individualized systemic treatment in pancreatic cancer is investigated. Also, the randomized controlled studies that have defined the neoadjuvant and surgical management of pancreatic cancer have been summarized.
Publikationsdatum
Forschungs-UpdatesBrain-Apparatus Communication: A Journal of Bacomics
Hinweise zu EEG, Mimik und Schlafverhalten
Der Eintrag bestätigt den Zusammenhang EEG—Mimik—Schlaf; ohne Volltext keine Details.
Thematische Nähe belegt keine Multimodal-Plattform des Unternehmens.
Changes in brain function and heart sound in acute sleep deprivation individuals.
Eintrag P0183 · CV-Jahr 2023 · Datumsgrundlage crossref_published-print. Daten werden mit der verfügbaren Genauigkeit (Jahr/Monat/Tag) angezeigt.
Paper-Abstract (Original)
Aims Sleep deprivation (SD) has become a health problem in modern society due to its adverse effects on different aspects. However, the relationship between sleep and cardiovascular system function remains unclear. Here we explored the changes occurring in the brain and the heart sounds after SD. Methods Ninety healthy adult men were recruited and subjected to 36 h of Sleep Deprivation (SD). They participated in a number of tests, including measurements of the heart sound, blood oxygen, and heart rate every 2 h. By using of principal component analysis to reduced the dimensionality of heart sound data. While the ALFF and ReHo indexes were measured via fMRI before and after SD. Correlation and regression analyses were used to reveal the relationship between fMRI and heart sound changes due to SD. Results In this study, there were no abnormal values in the heart rate and blood oxygen during 36 h of SD, whereas the intensity of heart sounds fluctuated significantly increased and decreased. The ALFF was increased in bilateral pericalcarine(Calcarine), left anterior cuneus, (Precuneus_L), right superior temporal gyrus(Temporal_Sup_R), left supplementary motor area (Supp_Motor_Area_L); However, it was reduced in the right medial superior frontal gyrus (Frontal_Sup_Medial_R), right dorsolateral superior frontal gyrus (Frontal_Sup_R) and left medial frontal gyrus (Frontal_Mid_L). The regression analysis uncovered that the intensity of the heart sound in the systole, s1, and s2 phase could be explained by Calcarine_L changes. Conclusion Acute sleep deprivation affects cardiac-brain axis and the specific brain regions. Calcarine_L changes during sleep deprivation are involved in regulating heart contractions.
Publikationsdatum
Forschungs-UpdatesFrontiers in artificial intelligence
Zeitmarken für Herztöne: automatische Segmentierung
Ein Audiowerkzeug gliedert den Herzzyklus und S1/S2; die Puls Oximeter-Frequenz dient als Referenz.
Publiziert 2024-01-11, Band/DOI 2023; kein vollständiges Diagnosesystem.
Construction and validation of a method for automated time label segmentation of heart sounds.
Eintrag P0180 · CV-Jahr 2024 · Datumsgrundlage crossref_published-online. Daten werden mit der verfügbaren Genauigkeit (Jahr/Monat/Tag) angezeigt.
Paper-Abstract (Original)
Heart sound detection technology plays an important role in the prediction of cardiovascular disease, but the most significant heart sounds are fleeting and may be imperceptible. Hence, obtaining heart sound information in an efficient and accurate manner will be helpful for the prediction and diagnosis of heart disease. To obtain heart sound information, we designed an audio data analysis tool to segment the heart sounds from single heart cycle, and validated the heart rate using a finger oxygen meter. The results from our validated technique could be used to realize heart sound segmentation. Our robust algorithmic platform was able to segment the heart sounds, which could then be compared in terms of their difference from the background. A combination of an electronic stethoscope and artificial intelligence technology was used for the digital collection of heart sounds and the intelligent identification of the first (S1) and second (S2) heart sounds. Our approach can provide an objective basis for the auscultation of heart sounds and visual display of heart sounds and murmurs.
Publikationsdatum
Forschungs-UpdatesSleep medicine
Schlafentzug und visuelle Konnektivität
Das Abstract beschreibt Veränderungen der funktionalen Konnektivität, Wachheit, Stimmung und Müdigkeit bei 60 gesunden Männern vor und nach 36 Stunden Schlafentzug.
Online 2024-11-22, Heft 2025-01; Konnektivitätsänderung ist keine Dissoziation.
The impact of sleep deprivation on the functional connectivity of visual-related brain regions.
Eintrag P0174 · CV-Jahr 2024 · Datumsgrundlage europepmc_firstPublicationDate. Daten werden mit der verfügbaren Genauigkeit (Jahr/Monat/Tag) angezeigt.
Paper-Abstract (Original)
Background Sleep deprivation(SD) is known to impair cognitive function and emotional regulation, however, its specific effects on the functional connectivity of visual-related brain regions remain unclear. Objectives This study aimed to investigate the impact of 36-h acute sleep deprivation on functional connectivity in visual neural circuits and its relationship with cognitive and emotional changes. Methods Sixty healthy male participants were assessed before and after 36 h of sleep deprivation using resting-state fMRI, the Psychomotor Vigilance Task (PVT), the Epworth Sleepiness Scale (ESS), and the Profile of Mood States (POMS). Functional connectivity changes were analyzed using paired t-tests and False Discovery Rate (FDR) correction. Key results Sleep deprivation significantly altered functional connectivity between the prefrontal cortex, hippocampus, and visual processing regions. These changes correlated with slower PVT reaction times, increased subjective sleepiness (ESS), and emotional disturbances (POMS), including heightened tension and reduced self-esteem. Conclusions The findings suggest that acute sleep deprivation impairs cognitive performance and emotional regulation by changing functional connectivity in key brain regions. These results may strengthen our understanding of neurobiology of SD and its potential negative effects.
Construction and validation of an automated time label segmentation method for infant cries.
Eintrag P0158 · CV-Jahr 2025 · Datumsgrundlage epub. Daten werden mit der verfügbaren Genauigkeit (Jahr/Monat/Tag) angezeigt.
AcknowledgementsAcknowledgments: We thank the undergraduate candidates SQC, WZH, LYF, who performed clinical examinations in community hospitals and provided valuable suggestions for this study. Dr Huang Kun provided valuable software segmentation experience for this study. The valuable support from the medical sound database from Chengdu Medical College (http://ama.cmc.edu.cn) and professional discussion from Chengdu Zhiju Data Science Technology Co., Ltd. (www.zjdatast.cn).
Beitrag nur "professional discussion"; die Datenbank gehört der Chengdu Medical College.
Paper-Abstract (Original)
Infant cries serve as critical indicators of an infant's physiological and psychological states, holding essential clinical value in distinguishing between normal and pathological conditions during early development. However, most studies on infant cries failed to segment between inhalation and exhalation during the crying analysis because segmentation remains great challenge. Therefore, we developed an audio data analysis tool capable of accurately segmenting inhalation and exhalation phases in infant cries, followed by extraction of the duration, frequency, and intensity parameters of each segment. Here, 226 sound clips of infants' cries were collected and analyzed. The results revealed the significant differences in sound parameters between premature and term infants. The whole process allows automatic identification and digital collection of infant cries, and it provides an objective method to evaluate the significance behind the cries.
Construction and Validation of an Automatic Segmentation Method for Respiratory Sound Time Labels.
Eintrag P0157 · CV-Jahr 2025 · Datumsgrundlage epub. Daten werden mit der verfügbaren Genauigkeit (Jahr/Monat/Tag) angezeigt.
AcknowledgmentsWe give special thanks for the valuable support from the medical sound database from Chengdu Medical College (http://ama.cmc.edu.cn) and the professional discussion from Chengdu Zhiju Data Science Technology Co. Ltd. (www.zjdatast.cn).
Beitrag nur "professional discussion"; die Datenbank gehört der Chengdu Medical College.
Paper-Abstract (Original)
Background In the field of respiratory system diseases, the utilization of respiratory sounds in auscultation plays a crucial role in the specific disease diagnosis. However, during the process of auscultation, the personal experiences and environmental factors may affect the decision making, leading to diagnostic errors. Therefore, to accurately and effectively obtain and analyze respiratory sounds can be positively contribute to the diagnosis and treatment of respiratory system diseases. Objectives Our aim was to develop an analytical method for the visualization and digitization of respiratory audio data, and to validate its capability to differentiate between various background diseases. Methods This study collected the respiratory sounds of patients admitted to the Department of General Medicine of Shanghai Changhai Hospital from June to December 2023. After strict screening according to the inclusion and exclusion criteria, a total of 84 patients were included. The research process includes using an electronic stethoscope to collect lung sounds from patients in a quiet environment. The patients expose their chests and lie flat. Sound data are collected at six landmark positions on the chest. The collected audio files are imported into an analysis tool for segmentation and feature extraction. Specific analysis methods include distinguishing heart sounds and respiratory sounds, segmenting respiratory sounds, determining the inspiratory and expiratory phases, and using a tool developed by the team for automatic segmentation encoding. Results We standardized the respiratory sounds of 84 patients and segmented multiple respiratory cycles. Following the localization and segmentation of the respiratory cycles based on label information, we calculated the average and standard deviation of the amplitude features for each segment of the respiratory cycle. The results indicated differences among various diseases. Conclusions The robust algorithm platform is capable of segmenting the respiratory sounds into inhale and exhale phases accordingly, then comparing the difference between different background diseases. This method provides objective evidence for the auscultation of respiratory sounds and visual display of breath sounds.
Publikationsdatum
Forschungs-UpdatesScientific reports
Geräuschstärke und Aufmerksamkeitsleistung
38 Studenten arbeiteten unter drei ansteigenden Geräuschstufen, gemessen mit fNIRS und Ausdruckskennwerten.
Feste aufsteigende Reihenfolge kann Reihenfolgeneffekte enthalten; keine universelle Lautstärke- oder Geräuschtherapie.
The impact of different decibels of ambient noise on attention.
Eintrag P0147 · CV-Jahr 2026 · Datumsgrundlage crossref_published-online. Daten werden mit der verfügbaren Genauigkeit (Jahr/Monat/Tag) angezeigt.
Paper-Abstract (Original)
Ambient noise is often perceived as a distractor; however, some individuals may benefit from certain levels of ambient noise to enhance cognitive performance. Despite this, the optimal range of ambient noise for improving attention remains unclear. To disclose this relationship, thirty-eight healthy college students were recruited to perform a 6 ⋅ 6 Schulte grid test under varying ambient noise levels. All participants performed the tasks under three noise conditions presented in a fixed order of increasing intensity (20-40 dB, 40-60 dB, and 60-80 dB). Functional near-infrared spectroscopy (fNIRS) was employed to measure dynamic changes in hemoglobin levels, while facial expressions and physiological signs were also assessed. The findings demonstrated that 40-60 dB group exhibited strongest visual brain functional connectivity. Among the three groups, the 40-60 dB group exhibited the highest values for anger expression, surprise expression, and heart rate (HR) (all p < 0.0001). Additionally, this group showed significantly higher heart rate variability (SDNN) compared to the 60-80 dB group (p < 0.05). The region of interest (ROI) pars triangularis Broca's area left~ pars triangularis Broca's area right revealed a significant difference (P = 0.004). Furthermore, the pairwise post hoc tests revealed the significant differences between the 20-40 dB group and 60-80 dB group (P = 0.007), as well as between the 40-60 dB group and 60-80 dB group (P = 0.017). In conclusion, moderate noise (40-60 dB) appears to induce an optimal level of arousal. In contrast, high-intensity noise (60-80 dB) likely prompts functional reorganization between the bilateral triangular parts of Broca's area to support cognitive control and interference suppression.The moderate intensity of noise may arouse the attention.
Publikationsdatum
Danksagung (professional discussion)International journal of psychology : Journal international de psychologie
fNIRS-Studie zu visuellen Reizen und Entscheidungen
Die Studie umfasste 300 Studierende im Alter von 18 bis 22 Jahren in drei Gruppen; visuelle Reize und Entscheidungen wurden mit fNIRS, Mimik und Vitalparametern verfolgt.
Explorative Studie, kein Werbeversprechen; Beitrag des Unternehmens nur "professional discussion".
The Effect of Culture Mix or Not Conflict Against the Decision Making-A fNIRS Study.
Eintrag P0145 · CV-Jahr 2026 · Datumsgrundlage epub. Daten werden mit der verfügbaren Genauigkeit (Jahr/Monat/Tag) angezeigt.
AcknowledgementsWe specially thank the valuable support from the medical sound database from Chengdu Medical College (http://ama.cmc.edu.cn) and professional discussion from Chengdu Zhiju Data Science Technology Co. Ltd. (www.zjdatast.cn).
Beitrag nur "professional discussion"; die Datenbank gehört der Chengdu Medical College.
Paper-Abstract (Original)
With increasing globalisation and deepening integration of local cultures, a growing number of product advertisements incorporate diverse, mixed cultural elements, designed to attract consumer attention and enhance purchase interest. However, the underlying mechanisms by which visual stimuli successfully influence consumer purchase behaviour remain poorly understood. In the present study, 300 college students aged 18-22 were recruited and randomly assigned to one of three between-subjects experiments (A, B and C), each comparing a control group (n = 50) with an experimental group (n = 50). The experiment employed a single-exposure paradigm, using functional near-infrared spectroscopy (fNIRS) to monitor changes in participant haemoglobin in brain cortical areas. Facial expressions and vital signs were simultaneously recorded in parallel. Based on these measurements, visual stimuli with mixed cultural elements collectively influence consumer decision-making through their intensity characteristics, potentially involving cognitive conflict processing and may be associated with enhanced emotional arousal and modulated autonomic nervous activity. These results provide exploratory evidence for the neural correlates underlying visual strategies in cross-cultural marketing and offer new methodological support for brand design and consumer cognition studies.
Einträge wie im CV erfasst; Publikationsdaten gemäß Zeitschriftenversion. Der Index wurde nicht extern geprüft; Jahresangaben aus dem CV. Publikationen sind persönliche bzw. gemeinsame Leistungen, keine Geschäftsfälle.Unterstützte PublikationenDanksagungen je Publikation geprüft.
Deduplizierung: P0263 und P0270 sind dieselbe Arbeit mit anderer Schreibweise (rs1344706/rsI344706), einfach gezählt; beide Originale bleiben erhalten.
2026 (11 Einträge)
Yutong Ma*, Yingfeng Tan*, Fan Xu*, Jiayi Chen, Yuxian Chen, Fangfang Liu, Meng Fan#, Qin Han#; (2026) The Impact of Different Severities of Anxiety on Decision-Making, Brain and Behaviour, 16, no. 9: e71704. https://doi.org/10.1002/brb3.71704
Hanrui Zeng, Qiongfang Cao, Peng Zhang, Yuhan Wang, Jing Wang, Xiechuan Weng#, Fan Xu#; (2026) Alterations in mood, cognitive behaviour and functional connectivity between brain regions in healthy adult males with acute total sleep deprivation. Physiol Behav. 2026 Aug 4:115459. doi: 10.1016/j.physbeh.2026.115459. Epub ahead of print. PMID: 42551724.
Min Huang, Fangfang Liu, Fan Xu#. (2026) Patience Is Needed to Uncover the Reasons Behind Social Cognitive Deficits in Heroin Abstainers. Biol Psychiatry. 2026 Aug 1;100(3):235-236. doi: 10.1016/j.biopsych.2026.05.017. PMID: 42419826.
Fangfang Liu, Fang Liu, Wen Wen, Yuhang Li, Yulin Duan, Shuang Wei, Peiyao Liu, Min Huang#, Fan Xu# (2026). The impact of different decibels of ambient noise on attention. Sci Rep. 2026 May 23. doi: 10.1038/s41598-026-54145-4. Epub ahead of print. PMID: 42177288.
Limei Wu, Jiang Li, Zhanglu Wang, Ye Liu, Xi Huang, Fan Xu# and Li Li# (2026) Status of unwanted pregnancy and contraceptive needs among women of childbearing age in Chengdu City: a cross-sectional study. Front. Glob. Women’s Health 7:1759010. doi: 10.3389/fgwh.2026.1759010, PMID:42037778;
Xi Chen, Lin Dao, Wenjun Huang, Bi Li, Xiaolan Wang, Zhengyu Chen, Fangfang Liu, Li Luo#, Fan Xu# (2026). Dynamic changes and functional analysis of the vaginal microbial communities in reproductively dysfunctional giant pandas. Vet J. 2026 Mar 28; 317:106660. doi:10.1016/j.tvjl.2026.106660. Epub ahead of print. PMID: 41912105.
Yan Zhang*, Shiyu Lei*, Fangfang Liu*, Xi Huang, Xuejun Xu, Lanying He, Jian Wang#, Fan Xu#(2026). Risk factors for plaque vulnerability in a community population: endothelial function and arterial stiffness indexes. Ann Vasc Surg. 2026 Jan 2:S0890-5096(25)00909-4. doi: 10.1016/j.avsg.2025.12.021. Epub ahead of print. PMID: 41485640. (Q3, IF=1.6)
Yi-Xiu Lin, Dan Li, Zhu Huang, Neng Huang, Shuang-Ming Shi, Fan Xu, Shi-Zheng Wu, Lei Chen, Cheng Huang; (2026) A randomized controlled trial of mild hyperbaric oxygen therapy on cognitive performance and sleep quality in healthy young adults at high altitude: Exploratory functional near-infrared spectroscopy study, J Travel Medicine and Infectious Disease, Volume 73, 2026,103008, ISSN 1477-8939,https://doi.org/10.1016/j.tmaid.2026.103008.
Wenhao Lv, Haiqi Xiang, Qiongfang Cao, Fangfang Liu, Fan Xu#, Xi Yang# (2025) The impact of positive encouragement on pre-school children while completing a constructive task, Acta Psychologica, Vol 261, 105831, ISSN 0001-6918, https://doi.org/10.1016/j.actpsy.2025.105831 PMID: 41175689, (Q2, IF=2.7)
Keyi Ma, Yi Wang, Yulin Zhou, Lan Chen, Tiecheng Zhang, Fan Xu#, Xiaoli Peng# (2025) Acoustic signatures of organic lesions and the role of artificial intelligence in voice disorder diagnostics. Digit Health. 2025 Oct 14;11:20552076251376264. doi: 10.1177/20552076251376264. PMID: 41116813; PMCID: PMC12535643.(Q1, IF=3.4)
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Qiongfang Cao*, Min Huang*, Xiuju Zhu*, Yuling Duan, Qicheng Shu, Xi Huang, Xun Guo, Fangfang Liu, Ziyu Hua#, Fan Xu# (2025). Construction and validation of an automated time label segmentation method for infant cries. BMC Pediatr 25, 726 (2025). https://doi.org/10.1186/s12887-025-06071-z (Q2, IF=2) PMID: 41039324;
Peng Zhang*, Kai Wen*, Huifeng Liu*, Jing Wang, Qin Han, Fangfang Liu, Xiechuan Weng# and Fan Xu# (2025) The impact of sleep deprivation on the functional connectivity of auditory-related brain regions. Brain Res Bull. 2025 Oct 15;231:111563. doi: 10.1016/j.brainresbull.2025.111563. Epub 2025 Oct 1. PMID: 41043695. (Q2, IF=3.7)
Yu Guan, Fan Meng, Xiaolin Ren, Siyuan Zhang, Chun Cao, Jingbing Lan, Qiongfang Cao, Tiecheng Zhang, Fan Xu & Tao Zhang , (2025) Exploration of the relationship between Graves’ eye disease and type 2 diabetes based on biomarkers, Hormones, https://doi.org/10.1007/s42000-025-00674-y , PMID: 40450128, (Q3, IF=2.5)
Wang zimai*, Cai yurui*, Wang xiaojun*, Wu shuyi, Cao yixin, Xu Fan# and Huang Min# (2025) The significance of an infant's cry: a narrative review of physiological, pathological, and analytical perspectives. Frontier in Pediatrics. 13:1558951. doi: 10.3389/fped.2025.1558951, PMID: 40416439, (Q2, IF=2.4)
Qiongfang Cao, Haiqi Xiang, Yuhan Wang, Fangfang Liu, Xiechuan Weng#, Fan Xu# (2025) Negative impact of insufficient sleep on the brain. Brain-Apparatus Communication: A Journal of Bacomics, 4(1). https://doi.org/10.1080/27706710.2025.2465538
Qicheng Shu*, Shiyu Tang*, Zhenhua Wu, Jiahuan Feng, Wenhao Lv, Min Huang# and Fan Xu# (2025) The impact of internet pornography addiction on brain function: a functional near-infrared spectroscopy study. Frontier in Human Neuroscience, 16 April 2025, Section Brain Health and Clinical Neuroscience, Volume 19 – 2025, https://doi.org/10.3389/fnhum.2025.1477914 , PMID:40309664 (Q2, IF=2.4)
Tiecheng Zhang, Xiaofeng Jing, Qiongfang Cao, Jie Yin, Xiechuan Weng#, Fan Xu# (2025) Non-invasive brain stimulation lighting the human life quality’s bulb, Brain-Apparatus Communication: A Journal of Bacomics, 4(1). https://doi.org/10.1080/27706710.2025.2482915
Mouse Meimei*, Gong Hongjie*, Liu Yifeng*, Xu Fan*, Zou Xianwei , Huang Min#, Yang Xi#, (2025) Changes in facial expressions can distinguish Parkinson’s disease via Bayesian inference, Frontiers in Neurology, VOL 6, doi:10.3389/fneur.2025.1533942, PMID: 40212609 (Q2, IF=2.7)
Qiongfang Cao, Xinyu Pan, Huan Li, Haiqi Xiang and Fan Xu* (2025) Construction and validation of the sleep ethogram. Brain-Apparatus Communication: A Journal of Bacomics, 4(1). https://doi.org/10.1080/27706710.2025.2475858
Tiecheng Zhang, Yingfeng Tan, Jiayi Chen, Xiaofeng Jing, Rong Meng, Fan Xu* (2025) Sedative Effect of White Noise on Prefrontal Cortex Lobe: A Randomized Controlled Study Based on Functional Near-Infrared Spectroscopy. Noise Health 2025; 27:26-32, PMID: 40029675(Q3, IF=1.3)
Yifeng Liu*, Hongjie Gong*, Meimei Mouse*, Fan Xu*, Xianwei Zou, Jingsheng Yang, Qingping Xue#, Min Huang#(2025) The Phonation test can distinguish the patient with Parkinson’s disease via Bayes Inference. Cognition Neurodynamic, 2025 Dec;19(1):18. DOI: 10.1007/s11571-024-10194-x. Epub 2025 Jan 9, PMID:39801919 (Q2, IF=3.1)
Qiongfang Cao, Peng Zhang, Fangfang Liu, Mengyan Jin, Yuhan Wang, Hanrui Zeng, Xiechuan Weng# and Xu F# (2025) The effect of deep magnetic stimulation on the cardiac-brain axis post-sleep deprivation: a pilot study. Front. Neurosci. 18:1464299. doi: 10.3389/fnins.2024.1464299, PMID: 39867450 (Q2, IF=3.2)
Gong, Cuifeng, Luo Gai, He Mengnan, Fan Xu, Ying Ma, Anqi Hu, Wei Wei#, Peng Chen#. The relationship between thermophysiology, endocrinology and behaviour in female giant pandas. Sci Rep 15, 30763 (2025). https://doi.org/10.1038/s41598-025-16111-4
Liu, Fangfang, Xu, Fan., Zhang, Yelan., Zou, Jifan., Ma, Yutong, & Meng, R. (2025). Psychological capital and learning burnout in college students: The mediating role of coping styles. Social Behavior and Personality: An international journal, 53(1), e14234
Xiechuan Weng, Kai Wen, Jin Guo, Peng Zhang, Yixin Zhang, Qiongfang Cao, Qin Han, Fan Xu# (2024) The impact of sleep deprivation on the functional connectivity of visual-related brain regions. Sleep Medicine, Vol 125, Jan 2025, Pages 155-167, https://doi.org/10.1016/j.sleep.2024.11.026, PMID:39612715 (Q1, IF=3.8)
Xiaofeng Jing, Ying Ma, Defu Li, Tiecheng Zhang, Haiqi Xiang, Fan Xu#, Yonghong Xia#.(2024) Integration of bile proteomics and metabolomics analyses reveals novel insights into different types of gallstones in a high-altitude area. BMC Gastroenterol 24, 330. https://doi.org/10.1186/s12876-024-03422-5, PMID: 39350090 (Q3, IF=2.5)
Qiongfang Cao, Huan Li, Xinyu Pan, Yuhan Wang, Peng Zhang, Lanying He, Jian Wang, Min Huang, Fan Xu* (2024) A Systematic Review and Meta-Analysis of the Predictive Power of China-PAR Against Cardiovascular Disease, Clin Med Res, 2024 Mar;22(1):28-36. doi: 10.3121/cmr.2024.1846. PMID: 38609143 (Q2, IF=1.4)
Haoyu Zhang, Jingyi Hu, Rong Meng, Fangfang Liu, Fan Xu*, Min Huang* (2024), A systematic review and meta-analysis comparing the diagnostic capability of automated breast ultrasound and contrast-enhanced ultrasound in breast cancer, Frontiers in Oncology, Sec. Breast Cancer, Volume 13 – 2023 https://doi.org/10.3389/fonc.2023.1305545, PMID: 38264749 (Q2, IF=4.7)
Liuying Li, Min Huang, Ling Dao, Xixi Feng, Yifeng Liu, Changyou Wei, Fangfang Liu, Jing Zhang* and Fan Xu* (2024) Construction and validation of a method for automated time label segmentation of heart sounds, Frontiers in Artificial Intelligence, Section Medicine and Public health, Volume 6-2023, https://doi.org/10.3389/frai.2023.1309750, PMID:38274051 (Q1, IF=5.1)
Yin Jie, Zhang Tiecheng, Li Dan, Xu Fan, Li Huan, Pan Xinyu, Fang Liu, Yongqi Zhao, Weng Xiechuan. (2024). Behavioral video coding analysis of chronic morphine administration in rats. Biomedical Reports, 21, 168. https://doi.org/10.3892/br.2024.1856
Qi Mei, Wanling Li, Huijing Feng, Junyan Zhang, Jian Li, Junping Yin, Veronika Lukacs-Kornek e, Christian Kurts, Shujuan Dai, Xiaoxiao Zhao, Qinglong Ai, Chunlei Yu, Fan Xu, Xiaoting Xi, Fang Liu, DaoYuan Song, Yaochang Wang, Lianmei Zhong, John. Wesson Ashford, Curtis Ashford, Xiaolei Liu, Hongxing Wang (2024) Chinese hospital staff in anxiety and depression: Not only comfort patients but also should be comforted - A nationwide cross-sectional study. Journal of Affective Disorders 360 (2024) 126-136.
Qiongfang Cao, Zhongrui Ma, Fangfang Liu, Yuhan Wang, Xiechuan Weng & Fan Xu* (2023): Correlation analysis between EEG data and facial expressions and sleep behaviors, Brain-Apparatus Communication: A Journal of Bacomics, DOI: 10.1080/27706710.2023.2208167,
Yanmei Xu, Xinyu Pan, Huan Li, Qiongfang Cao, Fan Xu* and Jianshu Zhang* (2023) Accuracy of Raman spectroscopy in the diagnosis of Alzheimer’s disease, Front. Psychiatry, 16 March 2023, Sec. Aging Psychiatry, Vol14-2023https://doi.org/10.3389/fpsyt.2023.1112615, PMID: 37009107 (Q2, IF=5.435)
Yan Zhang, Meng Wang, Xiaofeng Jing, Qiongfang Cao, Peng Zhang, Yuhan Wang, Fangfang Liu, Xuejun Xu, Jian Wang, Lanying He*, Fan Xu*(2023) Endothelial function and arterial stiffness indexes in subjects with carotid plaque and carotid plaque length: A subgroup analysis showing the relationship with hypertension and diabetes, J Stroke and Cerebrovascular Diseases, Vol 32, Issue 3, March 2023, 106986, https://doi.org/10.1016/j.jstrokecerebrovasdis.2023.106986, PMID:36669372 (Q3, IF=2.505)
Yan Zhang, Liqiong Yang, Peter Pohl, Fan Xu, Fangfang Liu, (2023), The white-browed laughingthrush (Pterorhinus sannio) did not pass the mirror self-recognition test, J Ethology Ecology & Evolution, http: //doi.org/10.1080/03949370.2023.2178032
Wang, Yuhan, Qiongfang Cao, Changyou Wei, Fan Xu, Peng Zhang, Hanrui Zeng, Yongcong Shao, Xiechuan Weng, and Rong Meng. (2023). "The Effect of Transcranial Electrical Stimulation on the Recovery of Sleep Quality after Sleep Deprivation Based on an EEG Analysis" Brain Sciences 13, no. 6: 933. https://doi.org/10.3390/brainsci13060933
Fan Xu, Min Huang, Yun Bai, Xueshi Yin, Jingzhe Yan, Fangfang Liu, Jie Chen*, Xiechuan Weng* (2022). Landmarks in pancreatic cancer studies. Cancer Cell Int 22, 383. https://doi.org/10.1186/s12935-022-02803-8 , PMID: 36476236 (Q2, IF=6.435)
Lanying He, Jian Wang, Feng Wang, Lili Zhang, Yinglin Liu, Fan XU*(2022) Depression symptoms and quality of life in empty-nest elderly among Chengdu: A cross-sectional study, Frontier in Psychiatry, 08 November, 2022, https://doi.org/10.3389/fpsyt.2022.10032, PMID:36424995 (Q2, IF=5.435)
Yan Zhang, Yun Bai, Jun Xie, Jian Wang, Lanying He, Min Huang, Fan Xu*(2022) Carotid plaque components and other carotid artery features associated with risk of stroke: A systematic review and meta-analysis, J Stroke and Cerebrovascular Diseases, Vol 31, Issue 12, December 2022, 106857, PMID:36334373 (Q3, IF=2.677)
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Yinglin Liu, Hongmei Peng, Jian Wang, Lanying He, Jinghan Xu, Min Zheng, Yao Xu and Fan Xu*(2022) Risk factors for early neurological deterioration in acute isolated pontine infarction without any causative artery stenosis, BMC Neurology, (2022) 22:332, http:// 10.1186/s12883-022-02861-5 , PMID:36057555 (Q3，IF=2.903)
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Tingting Pu, Guang Li, Yifan Liu, Xianwei Zou, Xixi Feng, Xiaolei Liu, Fan Xu* (2022) Speech Features analysis of Dysarthria in Patients with Parkinson’s Disease. Journal of Chengdu Medical College, Vol 17, No.2. https://kns.cnki.net/kcms/detail/51.1705.R.20220307.1445.002.html
Erst-/korrespondierender AutorCV-Eintrag P0197
Meng Wang, Yanxia Wen, Shicong Mo, Liqiong Yang, Xiaqing Chen, Man Luo, Hongdian Yu, Fan Xu*, Xianwei Zou*. (2022) Distinctive acoustic changes in speech in Parkinson's disease, J Computer Speech & Language, https://doi.org/10.1016/j.csl.2022.101384. (Q3，IF=3.252)
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Yang Zhang, Feng‐Qin Nie, Xiao‐Bo Huang, Weiwei Tang, Rong Hu, Wen‐Qiang Zhang, Jian‐Xiong Liu, Rong‐Hua Xu, Ya Liu, Dong Wei*, Tzung‐Dau Wang* and Xu Fan* (2022) High prevalence and low awareness of hyperuricemia in hypertensive patients among adults aged 50–79 years in Southwest China, BMC Cardiovascular Disorders, (2022) 22:2 https://doi.org/10.1186/s12872-021-02427-2 , PMID:34991490 (Q3, IF=2.298)
Jingsheng Yang, Quanhao Guo, Xianwei Zou ,Meng Wang, Yanxia Wen, Xiaqing Chen, Xiechuan Weng and Fan Xu* (2021) Correlation between head tremble and the severity of Parkinson’s disease, CNS Neuroscience and Therapeutics, 10 Nov 2021, https://doi.org/10.1111/cns.13753, PMID:34758102 (Q1, IF=5.243)
Lanying He, Jian Wang, Lili Zhang, Wang Zhao, Xiechuan Weng, Fan Xu*(2021) The length of susceptibility vessel sign predicts early neurological deterioration in minor acute ischemic stroke with large vessel occlusion, BMC Neurology, 21, 421(2021). https://doi.org/10.1186/s12883-021-02455-7, PMID:34715818 (Q3, IF=2.474)
Liqiong YANG*, Xiangling CHEN*, Quanhao GUO*, Jing ZHANG*, Man LUO, Xiaqing CHEN, Yanxia WEN, Xianwei ZOU^, Fan XU* (2021) Changes in facial expressions in patients with Parkinson’s disease during the phonation test and their correlation with disease severity, Computer speech and language, online 4 September 2021, 101286, https://doi.org/10.1016/j.csl.2021.101286, (Q3, IF=1.899)
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Erst-/korrespondierender AutorCV-Eintrag P0210
Jing Zhang,Xiangzhou Wang, Guangming Ni, Juanxiu Liu, Ruqian Hao, Lin Liu,Yong Liu, Xiaohui Du, Fan Xu*(2021) Fast and accurate automated recognition of the dominant cells from fecal images based on Faster R-CNN, Sci Rep 11, 10361. PMID:33990662 (Q1, IF=3.998)
Yunxi Wang, Qingping Xue, Xixi Feng, Guogang Xing, Fan Xu* (2021) Research Progress of Optogenetics in the treatment of Neurological Disease, Acta Laser Biology Sinca, Vol 30, No2, April 2021
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Erst-/korrespondierender AutorCV-Eintrag P0215
YANG Jinju, ZOU Xianwei, YU Jianping, LIU Xiaolei, XU Fan* (2020). Mechanisms and applications of physical therapy in Alzheimer's disease. International Journal of Geriatrics, Vol 41 No.4, P262-265 (chinesisch)
Erst-/korrespondierender AutorCV-Eintrag P0216
Shu YANG*, Fengbo WANG*, Liqiong YANG*, Fan XU*, Man LUO, Xiaqing CHEN, Xixi Feng#, & Xianwei ZOU#,（2020）The Physical significance of acoustic parameters and its clinical significance of dysarthria in Parkinson’s disease,Sci Rep,10,11776 (2020). https://doi.org/10.1038/s41598-020-68754-0, PMID:32678256 (Q1, IF=3.998)
Yan ZHANG, Greg Mirt, Fan XU#, Fangfang LIU#, (2020) The importance of Motacilla Alba behavior on hitting its own mirror reflection, Journal of Zoological Research, Vol 1, Issue 03, p5, DOI: https://doi.org/10.30564/jzr.v1i3.1977
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Yuxi Duan, Liqiong YANG, Fangfang LIU, Shu YANG, Fan XU*(2019), Are we used the appropriate therapy regimens on advanced pancreatic cancer? J Drug and drug abuse, Vol 1, Issue 1,2019, http://dx.doi.org/10.31487/j.DDA.2019.01.01 PMID: (Correspondent Author)
Jie Chen, Linli Chen, Jianping Yu, Yanmei Xu, Xiaohui Wang, Ziqian Zeng, Ning Liu, Fan Xu# and Shu Yang, Meta-analysis of current chemotherapy regimens in advanced pancreatic cancer to prolong survival and reduced treatment-associated toxicities, Molecular Medicine Report, 2019. 19(1): p. 477-489, PMID:30431091 (Q3, IF=1.851)
Yang Zhang, Li-Sha Hou, Wei-Wei Tang, Fan Xu, Rong-Hua Xu, Xin Liu, Ya Liu, Jian-Xiong Liu, Yan-Jing Yi, Tai-Shang Hu, Rong Hu, Tzung-Dau Wang & Xiao-Bo Huang, High prevalence of obesity-related hypertension among adults aged 40 to 79 years in Southwest China, Scientific report, https://doi.org/10.1038/s41598-019-52132-6
Fan X#, Jie C, Yushuang D, Linli C, Jing Y, Zhongrui M, Jianping Y, Jiayuan P, Shu Y, Wenwen L and Ronghua X (2018), Approaching to the essence of major depressive disorder, Edelweiss Psyi Open Access,2018,2:15-17
Fan Xu , Lei SUN et al (2016) Deep brain stimulation of pallidal versus subthalamic for patients with Parkinson disease: a meta-analysis of controlled clinical trials, Neuropsychiatric Disease and Treatment 2016: Volume 2016:12 P1435-1444. https://dx.doi.org/10.2147/NDT.S105513, PMID:27382286 (Q3, IF=1.867)
Qinming.Z, Xu F, et al (2014) The Mutual Influences between Depressed Macaca fascicularis Mothers and Their Infants. PLoS ONE9(3):e89931.doi:10.1371 /journal.pone.0089931, PMID:24599092 (Q1, IF=3.234)
Xie L, Xu F, Liu S, Ji Y, Zhou Q, et al. (2013) Age- and Sex-Based Hematological and Biochemical Parameters for Macaca fascicularis. PLoS ONE 8(6): e64892. doi:10.1371/journal.pone.0064892, PMID:23762263 (Q1, IF=3.534)
Xin L, Xu F., Liang.X.,et al (2013) Depression-Like Behavioral Phenotypes by Social and Social Plus Visual Isolation in the Adult Female Macaca Fascicularis. PLoS ONE 8(9): e73293. doi:10.1371/journal.pone.0073293 , PMID: 24023857 (Q1, IF=3.534)
Liang.X. Shig.L, Xu F et al, (2013) ,Normal Thoracic Radiographic Appearance of the Cynomolgus Monkey (Macaca fascicularis);PLoS ONE 2014 Jan8:9(1): e84599.DOI: 10.1371/journal.pone.0084599
Ji Y, Xie L, Liu S, Cheng K, Xu F. et al (2013) Correlation of thoracic radiograph measurements with age in adolescent Chinese rhesus macaques (Macaca mulatta). J Am Assoc Lab Anim Sci 52, 78-82 (2013).
AutorenrolleCV-Eintrag P0266
2012 (3 Einträge)
Xu F, Xie L, Li X, Li Q, Wang T, et al. (2012) Construction and Validation of a Systematic Ethogram of Macaca fascicularis in a Free Enclosure. PLoS ONE 7(5): e37486. doi:10.1371/journal.pone.0037486, PMID:22662158 (Q1, IF=3.730)
Xu F et al (2012) Influence of reared baby or not on the social behavior of female Macaca fascicularis in free enclosure. Acta Laboratorium animals science since.20(3):18-22 (Chinese)
Erst-/korrespondierender AutorCV-Eintrag P0242
Xin.L, Liang.X, Xu F et al (2012) Daily Time Budgets Of The Capative Adult Female Macaca fascicularis, Sichuan Journal of Zoology, 31(05): 798-8021 (Chinese)
AutorenrolleCV-Eintrag P0267
2007 (1 Eintrag)
Xu F et al (2007) Establishment of spinal cord injury models and its evaluation of neural function after spinal cord injury ,J Trauma Surgery, 1:91-93 (Chinese)
Erst-/korrespondierender AutorCV-Eintrag P0244
2006 (2 Einträge)
Xu F et al (2006) Thinking about relevant problems concerning low temperature of intravenous infusion fluids,J Chinese Nursing Research,20(5): 1384 (Chinese)
Erst-/korrespondierender AutorCV-Eintrag P0245
Xu F et al (2006) The progress of cell transplantation in spinal cord injury, J Sichuan Physiology,28(3),123-125(Chinese)
Erst-/korrespondierender AutorCV-Eintrag P0246
Software-Copyrights (CV-Einträge)
Die Einträge sind dem akademischen Lebenslauf von Xu Fan entnommen. Namen, Versionsnummern und Registrierungsnummern folgen der Quelle und repräsentieren keine verifizierte Softwarefunktion. Verifizierbare Zertifikate oder Rechteinhaber liegen nicht vor; eine Zuordnung zu Unternehmensvermögen erfolgt daher nicht. Eine Software-Copyright-Registrierung ist keine Medizinprodukt-Zulassung und bestätigt keine klinische Wirksamkeit.
Klinische Datenerfassung und DOI-Abruf, Reg.-Nr. 2019SR0027932, 2019
